Xq28 and lupus: IRAK1 or MECP2?

Eitemau Tebyg

• Fine Mapping of Xq28: Both MECP2 and IRAK1 Contribute to Risk for Systemic Lupus Erythematosus in Multiple Ancestral Groups
  gan: Kaufman, Kenneth M., et al.
  Cyhoeddwyd: (2012)
• Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse
  gan: Koelsch, Kristi A., et al.
  Cyhoeddwyd: (2013)
• Overexpression of methyl-CpG-binding protein 2 and autoimmunity: Evidence from MECP2 duplication syndrome, lupus, MECP2 transgenic and Mecp2 deficient mice
  gan: Sawalha, Amr H.
  Cyhoeddwyd: (2013)
• Reply to Sawalha: Evidence for IRAK1 is not evidence against MECP2
  gan: Jacob, Chaim O., et al.
  Cyhoeddwyd: (2009)
• Structural variation in Xq28: MECP2 duplications in 1% of patients with unexplained XLMR and in 2% of male patients with severe encephalopathy
  gan: Lugtenberg, Dorien, et al.
  Cyhoeddwyd: (2009)