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Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function
Neurog3 (Neurogenin 3 or Ngn3) is both necessary and sufficient to induce endocrine islet cell differentiation from embryonic pancreatic progenitors. Since robust Neurog3 expression has not been detected in hormone-expressing cells, Neurog3 is used as an endocrine progenitor marker and regarded as d...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701002/ https://ncbi.nlm.nih.gov/pubmed/19487660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904247106 |
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