γ-Actin is required for cytoskeletal maintenance but not development

β(cyto)-Actin and γ(cyto)-actin are ubiquitous proteins thought to be essential building blocks of the cytoskeleton in all non-muscle cells. Despite this widely held supposition, we show that γ(cyto)-actin null mice (Actg1(−/−)) are viable. However, they suffer increased mortality and show progressi...

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Hlavní autoři: Belyantseva, Inna A., Perrin, Benjamin J., Sonnemann, Kevin J., Zhu, Mei, Stepanyan, Ruben, McGee, JoAnn, Frolenkov, Gregory I., Walsh, Edward J., Friderici, Karen H., Friedman, Thomas B., Ervasti, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701000/
https://ncbi.nlm.nih.gov/pubmed/19497859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900221106
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