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Integrin β(1)-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

The development of metastases is an extended and inefficient process involving multiple steps. The last of these involves the growth of micrometastases into macroscopic tumors. We show here that intravenously injected, nonmetastatic cancer cells cease proliferating after extravasating into the paren...

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Detalhes bibliográficos
Main Authors: Shibue, Tsukasa, Weinberg, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700942/
https://ncbi.nlm.nih.gov/pubmed/19502425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904227106
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