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Protein-binding elements establish in the oocyte the primary imprint of the Prader-Willi/Angelman syndromes domain

Imprinting of the PWS/AS 2.4 Mb domain in the human is controlled by a paternally active imprinting center (PWS-IC). PWS-IC on the maternal allele is methylated and inactivated by an 880-bp sequence (AS-IC) located 30 kb upstream. In this communication, we report the identification of 7 cis acting e...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kaufman, Yotam, Heled, Maya, Perk, Jonathan, Razin, Aharon, Shemer, Ruth
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700935/
https://ncbi.nlm.nih.gov/pubmed/19506242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902087106
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