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Protein-binding elements establish in the oocyte the primary imprint of the Prader-Willi/Angelman syndromes domain
Imprinting of the PWS/AS 2.4 Mb domain in the human is controlled by a paternally active imprinting center (PWS-IC). PWS-IC on the maternal allele is methylated and inactivated by an 880-bp sequence (AS-IC) located 30 kb upstream. In this communication, we report the identification of 7 cis acting e...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700935/ https://ncbi.nlm.nih.gov/pubmed/19506242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902087106 |
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