JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation

The p53 tumor suppressor plays a central role in integrating cellular responses to various stresses. Tight regulation of p53 is thus essential for the maintenance of genome integrity and normal cell proliferation. Currently, several ubiquitin ligases, including the single-subunit RING-finger types—M...

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Detalhes bibliográficos
Main Authors: Sun, Luyang, Shi, Lei, Li, Wenqian, Yu, Wenhua, Liang, Jing, Zhang, Hua, Yang, Xiaohan, Wang, Yan, Li, Ruifang, Yao, Xingrong, Yi, Xia, Shang, Yongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700892/
https://ncbi.nlm.nih.gov/pubmed/19509332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901864106
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