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The C-terminus of complement factor H is essential for host cell protection

Complement is a powerful self-amplifying system of innate immune defence with the capacity to eliminate microbes directly. Factor H is a central regulator in plasma which protects host tissue from complement mediated damage. Here we characterize the relevance of surface attached factor H, and study...

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Bibliografiske detaljer
Main Authors: Józsi, Mihály, Oppermann, Martin, Lambris, John D., Zipfel, Peter F.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700862/
https://ncbi.nlm.nih.gov/pubmed/17208302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2006.12.001
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