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Two PEST-like motifs regulate Ca2+/calpain-mediated cleavage of the Ca(V)β(3) subunit and provide important determinants for neuronal Ca2+ channel activity
Increase in intracellular Ca(2+) due to voltage-gated Ca(2+) (Ca(V)) channel opening represents an important trigger for a number of second-messenger mediated effects ranging from neurotransmitter release to gene activation. Ca(2+) entry occurs through the principal pore-forming protein, but several...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700823/ https://ncbi.nlm.nih.gov/pubmed/16706839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2006.04749.x |
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