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Nanosecond photoreduction of inducible nitric oxide synthase by a Ru-diimine electron tunneling wire bound distant from the active site

A Ru-diimine wire, [(4,4’,5,5’-tetramethylbipyridine)(2)Ru(F(9)bp)](2+) (tmRu-F(9)bp, where F(9)bp is 4-methyl-4’-methylperfluorobiphenylbipyridine), binds tightly to the oxidase domain of inducible nitric oxide synthase (iNOSoxy). The binding of tmRu-F(9)bp is independent of tetrahydrobiopterin, ar...

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Detalhes bibliográficos
Main Authors: Whited, Charlotte A., Belliston-Bittner, Wendy, Dunn, Alexander R., Winkler, Jay R., Gray, Harry B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700734/
https://ncbi.nlm.nih.gov/pubmed/19427703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2009.04.001
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