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Skin-Derived TSLP Triggers Progression from Epidermal-Barrier Defects to Asthma

Asthma is a common allergic lung disease frequently affecting individuals with a prior history of eczema/atopic dermatitis (AD); however, the mechanism underlying the progression from AD to asthma (the so-called “atopic march”) is unclear. Here we show that, like humans with AD, mice with skin-barri...

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Autors principals: Demehri, Shadmehr, Morimoto, Mitsuru, Holtzman, Michael J., Kopan, Raphael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700555/
https://ncbi.nlm.nih.gov/pubmed/19557146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000067
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