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Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants

The function of phosphatidylcholine (PC) in the bacterial cell envelope remains cryptic. We show here that productive interaction of the respiratory pathogen Legionella pneumophila with host cells requires bacterial PC. Synthesis of the lipid in L. pneumophila was shown to occur via either phospholi...

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Detalhes bibliográficos
Main Authors: Conover, Gloria M, Martinez-Morales, Fernando, Heidtman, Matthew I., Luo, Zhao-Qing, Tang, May, Chen, Cui, Geiger, Otto, Isberg, Ralph R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700552/
https://ncbi.nlm.nih.gov/pubmed/17979985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2007.01066.x
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