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Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members
It is still unclear whether the BH3-only protein Puma (p53 up-regulated modulator of apoptosis) can prime cells to death and render antiapoptotic BH3-binding Bcl-2 homologues necessary for survival through its ability to directly interact with proapoptotic Bax and activate it. In this study, we prov...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700382/ https://ncbi.nlm.nih.gov/pubmed/19380879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200809153 |
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