Inactivation of Chibby affects function of motile airway cilia

Chibby (Cby) is a conserved component of the Wnt–β-catenin pathway. Cby physically interacts with β-catenin to repress its activation of transcription. To elucidate the function of Cby in vertebrates, we generated Cby(−/−) mice and found that after 2–3 d of weight loss, the majority of mice die befo...

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Bibliographic Details
Main Authors: Voronina, Vera A., Takemaru, Ken-Ichi, Treuting, Piper, Love, Damon, Grubb, Barbara R., Hajjar, Adeline M., Adams, Allison, Li, Feng-Qian, Moon, Randall T.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700371/
https://ncbi.nlm.nih.gov/pubmed/19364920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200809144
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