Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice

Certain polymorphisms reduce serotonin (5-HT) reuptake transporter (5-HTT) function and increase susceptibility to psychiatric disorders. Heterozygous (5-HTT(+/−)) deficient mice, models for humans with these polymorphisms, have elevated brain 5-HT concentrations and behavioral abnormalities. Since...

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Autori principali: Basselin, Mireille, Fox, Meredith A., Chang, Lisa, Bell, Jane M., Greenstein, Dede, Chen, Mei, Murphy, Dennis L., Rapoport, Stanley I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700347/
https://ncbi.nlm.nih.gov/pubmed/19145225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.227
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