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Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats
Evidence that brain glutamatergic activity is pathologically elevated in bipolar disorder suggests that mood stabilizers are therapeutic in the disease in part by downregulating glutamatergic activity. Such activity can involve the second messenger, arachidonic acid (AA, 20:4n-6). We tested this hyp...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2564799/ https://ncbi.nlm.nih.gov/pubmed/18461450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-008-9700-2 |
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