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Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats

Evidence that brain glutamatergic activity is pathologically elevated in bipolar disorder suggests that mood stabilizers are therapeutic in the disease in part by downregulating glutamatergic activity. Such activity can involve the second messenger, arachidonic acid (AA, 20:4n-6). We tested this hyp...

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Bibliografiske detaljer
Main Authors: Basselin, Mireille, Chang, Lisa, Chen, Mei, Bell, Jane M., Rapoport, Stanley I.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564799/
https://ncbi.nlm.nih.gov/pubmed/18461450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-008-9700-2
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