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(131)I anti-CD45 radioimmunotherapy effectively targets and treats T-cell non-Hodgkin lymphoma

Radioimmunotherapy (RIT) options for T-cell non-Hodgkin lymphomas (T-NHLs) are limited. We evaluated anti-CD45-RIT in human (h) and murine (m) T-NHL. CD45 was highly expressed on hT-NHL patient samples (median, 2.3 × 10(5) antigen-binding capacity units/cell) and hT-NHL cell lines (3.4 × 10(5) CD45...

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Bibliografiske detaljer
Main Authors: Gopal, Ajay K., Pagel, John M., Fromm, Jonathan R., Wilbur, Shani, Press, Oliver W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700326/
https://ncbi.nlm.nih.gov/pubmed/19332764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-205476
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