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TGF-β receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-β
TGF-β is a pluripotent cytokine that mediates its effects through a receptor composed of TGF-β receptor type II (TGFBR2) and type I (TGFBR1). The TGF-β receptor can regulate Smad and nonSmad signaling pathways, which then ultimately dictate TGF-β's biological effects. We postulated that control...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700179/ https://ncbi.nlm.nih.gov/pubmed/19339207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2009.02.001 |
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