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Does the learning deficit observed under an Incremental Repeated Acquisition schedule of reinforcement in Ts65Dn mice, a model for Down syndrome, change as they age?

The Ts65Dn mouse is partly trisomic at chromosome 16 and is considered to be a valid mouse model of human Down syndrome. Prior research using an incremental repeated acquisition (IRA) schedule of reinforcement has revealed that there is a significant learning deficit in young, adult Ts65Dn mice comp...

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Autors principals: Sanders, Nichole C., Williams, D. Keith, Wenger, Galen R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700176/
https://ncbi.nlm.nih.gov/pubmed/19409933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2009.04.031
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