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Probing the interface in a human co-chaperonin heptamer: residues disrupting oligomeric unfolded state identified

BACKGROUND: The co-chaperonin protein 10 (cpn10) assists cpn60 in the folding of nonnative polypeptides in a wide range of organisms. All known cpn10 molecules are heptamers of seven identical subunits that are linked together by β-strand interactions at a large and flexible interface. Unfolding of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Guidry, Jesse J, Shewmaker, Frank, Maskos, Karol, Landry, Samuel, Wittung-Stafshede, Pernilla
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC270013/
https://ncbi.nlm.nih.gov/pubmed/14525625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-4-14
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