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The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer

Mutations within the BRCA1 tumor suppressor gene occur frequently in familial epithelial ovarian carcinomas but they are a rare event in the much more prevalent sporadic form of the disease. However, decreased BRCA1 expression occurs frequently in sporadic tumors, and the magnitude of this decrease...

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Detalhes bibliográficos
Main Authors: McCoy, Marcia L, Mueller, Christopher R, Roskelley, Calvin D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC270004/
https://ncbi.nlm.nih.gov/pubmed/14613551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-1-72
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