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Overexpression of the p53 inhibitor MDM4 in Head and Neck Squamous Carcinomas
The p53 tumor suppressor is mutated in the majority of human tumors. MDM2, a well-known inhibitor of p53, is overexpressed in a large number of tumors suggesting that increased levels of MDM2 also contribute to tumorigenesis. A novel p53 inhibitor, MDM4, was more recently identified. The role of MDM...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699677/ https://ncbi.nlm.nih.gov/pubmed/17651783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2007.03.005 |
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