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Overexpression of the p53 inhibitor MDM4 in Head and Neck Squamous Carcinomas

The p53 tumor suppressor is mutated in the majority of human tumors. MDM2, a well-known inhibitor of p53, is overexpressed in a large number of tumors suggesting that increased levels of MDM2 also contribute to tumorigenesis. A novel p53 inhibitor, MDM4, was more recently identified. The role of MDM...

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Main Authors: Valentin-Vega, Yasmine A., Barboza, Juan A., Chau, Gilda P., El-Naggar, Adel K., Lozano, Guillermina
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699677/
https://ncbi.nlm.nih.gov/pubmed/17651783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2007.03.005
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