Physico-Chemical Characteristics of Lipoplexes Influence Cell Uptake Mechanisms and Transfection Efficacy

BACKGROUND: Formulation of DNA/cationic lipid complexes (lipoplexes) designed for nucleic acid delivery mostly results in positively charged particles which are thought to enter cells by endocytosis. We recently developed a lipoplex formulation called Neutraplex that allows preparation of both catio...

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Bibliografiska uppgifter
Huvudupphovsmän: Resina, Sarah, Prevot, Paul, Thierry, Alain R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699663/
https://ncbi.nlm.nih.gov/pubmed/19557145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006058
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