Evaluation of bovine, cold-adapted human, and wild-type human parainfluenza type 3 viruses in adult volunteers and in chimpanzees.

In an attempt to evaluate the level of attenuation of live parainfluenza type 3 virus (PIV3) vaccine candidates, we compared the responses of partially immune adult volunteers inoculated intranasally with 10(6) to 10(7) 50% tissue culture infective dose (TCID50) of bovine PIV3 (n = 18) or cold-adapt...

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Библиографические подробности
Главные авторы: Clements, M L, Belshe, R B, King, J, Newman, F, Westblom, T U, Tierney, E L, London, W T, Murphy, B R
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC269965/
https://ncbi.nlm.nih.gov/pubmed/1650789
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