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Cleavage of a model DNA replication fork by a Type I restriction endonuclease

Cleavage of a DNA replication fork leads to fork restoration by recombination repair. In prokaryote cells carrying restriction–modification systems, fork passage reduces genome methylation by the modification enzyme and exposes the chromosome to attack by the restriction enzyme. Various observations...

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Detalhes bibliográficos
Main Authors: Ishikawa, Ken, Handa, Naofumi, Kobayashi, Ichizo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699502/
https://ncbi.nlm.nih.gov/pubmed/19357093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp214
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