Lactate Dehydrogenase-Elevating Virus Induces Systemic Lymphocyte Activation via TLR7-Dependent IFNα Responses by Plasmacytoid Dendritic Cells

BACKGROUND: Lactate dehydrogenase-elevating virus (LDV) is a natural infectious agent of mice. Like several other viruses, LDV causes widespread and very rapid but transient activation of both B cells and T cells in lymphoid tissues and the blood. The mechanism of this activation has not been fully...

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Bibliographic Details
Main Authors: Ammann, Christoph G., Messer, Ronald J., Peterson, Karin E., Hasenkrug, Kim J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699471/
https://ncbi.nlm.nih.gov/pubmed/19568424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006105
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