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Adenosine closes the K(+) channel K(Ca)3.1 in human lung mast cells and inhibits their migration via the adenosine A(2A) receptor
Human lung mast cells (HLMC) express the Ca(2+)-activated K(+) channel K(Ca)3.1, which opens following IgE-dependent activation. This hyperpolarises the cell membrane and potentiates both Ca(2+) influx and degranulation. In addition, blockade of K(Ca)3.1 profoundly inhibits HLMC migration to a varie...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
WILEY-VCH Verlag
2007
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699420/ https://ncbi.nlm.nih.gov/pubmed/17474152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200637024 |
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