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Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells

Small interfering RNAs (siRNAs) directed to gene promoters can silence genes at the transcriptional level. siRNA-directed transcriptional silencing (RdTS) was first described in plants and yeasts and more recently in mammalian cells. RdTS has been associated with the induction of epigenetic changes...

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Detaylı Bibliyografya
Asıl Yazarlar: Napoli, Sara, Pastori, Chiara, Magistri, Marco, Carbone, Giuseppina M, Catapano, Carlo V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699364/
https://ncbi.nlm.nih.gov/pubmed/19461583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.139
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