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Caged O-phosphorothioyl amino acids as building blocks for Fmoc-based solid phase peptide synthesis

The synthesis of 1-(2-nitrophenylethyl) caged O-phosphorothioylserine, -threonine and –tyrosine derivatives is reported. These amino acid building blocks can be directly incorporated into peptides by Fmoc-based solid phase synthesis as their pentafluorophenyl esters or as symmetric anhydrides. Upon...

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Detalhes bibliográficos
Main Authors: Aemissegger, Andreas, Carrigan, Christina N., Imperiali, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699315/
https://ncbi.nlm.nih.gov/pubmed/19543448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.03.023
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