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Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation

The synthesis of glycosylated Fmoc amino acids by reaction of mono- and disaccharide peracetates with Fmoc amino acids having free carboxyl groups was rapidly promoted by Lewis acids (SnCl(4), BF(3)·Et(2)O) under microwave irradiation. The products are useful building blocks for the synthesis of gly...

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Detalhes bibliográficos
Main Authors: Yao, Nianhuan, Fung, Gabriel, Malken, Hamed, Ye, Long, Lam, Kit S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207739/
https://ncbi.nlm.nih.gov/pubmed/20832778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.07.040
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