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Studies on Paraherquamide Biosynthesis: Synthesis of Deuterium-Labeled 7-Hydroxy-Pre-Paraherquamide, a Putative Precursor of Paraherquamides A, E & F

The stereocontrolled, asymmetric synthesis of triply deuterium-labeled 7-hydroxy-pre-paraherquamide (27) was accomplished, employing a diastereoselective intramolecular S(N)2′ cyclization strategy. The deuterium-labeled substrate was interrogated in a precursor incorporation experiment in the parahe...

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Bibliografiske detaljer
Main Authors: Sommer, Konrad, Williams, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699280/
https://ncbi.nlm.nih.gov/pubmed/20161298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.08.102
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