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Role of the interdomain linker in distance determination for remote cleavage by homing endonuclease I-TevI

I-TevI is a modular intron-encoded endonuclease, consisting of an N-terminal catalytic and a C-terminal DNA-binding domain, joined by a 75-amino acid linker. This linker can be divided into three regions, from N- to C-terminal: the deletion intolerant (DI) region; the deletion tolerant (DT) region;...

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Detalhes bibliográficos
Main Authors: Liu, Qingqing, Dansereau, John T., Puttamadappa, Shadakshara S., Shekhtman, Alexander, Derbyshire, Victoria, Belfort, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699217/
https://ncbi.nlm.nih.gov/pubmed/18499124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.04.047
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