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Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery

The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian cells, binds the tumor suppressor protein BRCA2. Here, we describe a new function for yeast Sem1. We show that sem1 mutants are impaired in messenger RNA (mRNA) export and...

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書誌詳細
主要な著者: Faza, Marius Boulos, Kemmler, Stefan, Jimeno, Sonia, González-Aguilera, Cristina, Aguilera, Andrés, Hurt, Ed, Panse, Vikram Govind
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699155/
https://ncbi.nlm.nih.gov/pubmed/19289793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200810059
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