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Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian cells, binds the tumor suppressor protein BRCA2. Here, we describe a new function for yeast Sem1. We show that sem1 mutants are impaired in messenger RNA (mRNA) export and...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699155/ https://ncbi.nlm.nih.gov/pubmed/19289793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200810059 |
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