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Emerging trends in plasma‐free manufacturing of recombinant protein therapeutics expressed in mammalian cells

Mammalian cells are the expression system of choice for therapeutic proteins, especially those requiring complex post‐translational modifications. Traditionally, these cells are grown in medium supplemented with serum and other animal‐ or human‐derived components to support viability and productivit...

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Hlavní autoři: Grillberger, Leopold, Kreil, Thomas R., Nasr, Sonia, Reiter, Manfred
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY‐VCH Verlag 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699044/
https://ncbi.nlm.nih.gov/pubmed/19226552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.200800241
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