IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells

BACKGROUND: Colorectal cancer is the third most common cancer in the western world. Chemotherapy is often ineffective to treat the advanced colorectal cancers due to the chemo-resistance. A major contributor to chemo-resistance is tumour-derived inhibition or avoidance of apoptosis. Insulin-like gro...

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Hlavní autoři: Yang, Shi Yu, Bolvin, Capucine, Sales, Kevin M, Fuller, Barry, Seifalian, Alexander M, Winslet, Marc C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698923/
https://ncbi.nlm.nih.gov/pubmed/19460165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-158
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