Identification of eIF2Bγ and eIF2γ as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach

The 5′-untranslated region of hepatitis C virus (HCV) is highly conserved, folds into a complex secondary structure, and functions as an internal ribosome entry site (IRES) to initiate translation of HCV proteins. We have developed a selection system based on a randomized hairpin ribozyme gene libra...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Krüger, Martin, Beger, Carmela, Li, Qiang-Xin, Welch, Peter J., Tritz, Richard, Leavitt, Mark, Barber, Jack R., Wong-Staal, Flossie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26988/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10900014/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.15.8566
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