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Cell Density-Dependent Inhibition of Epidermal Growth Factor Receptor Signaling by p38α Mitogen-Activated Protein Kinase via Sprouty2 Downregulation

Contact inhibition is a fundamental process in multicellular organisms aimed at inhibiting proliferation at high cellular densities through poorly characterized intracellular signals, despite availability of growth factors. We have previously identified the protein kinase p38α as a novel regulator o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Swat, Aneta, Dolado, Ignacio, Rojas, Jose Maria, Nebreda, Angel R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698726/
https://ncbi.nlm.nih.gov/pubmed/19364817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01955-08
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