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The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution

During microRNA (miRNA) biogenesis, one strand of a ∼21–22-nucleotide RNA duplex is preferentially selected for entry into a silencing complex. The other strand, known as the miRNA* species, has typically been assumed to be a carrier strand. Here we show that, although Drosophila melanogaster miRNA*...

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Bibliographische Detailangaben
Hauptverfasser: Okamura, Katsutomo, Phillips, Michael D, Tyler, David M, Duan, Hong, Chou, Yu-ting, Lai, Eric C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698667/
https://ncbi.nlm.nih.gov/pubmed/18376413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1409
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