Rosiglitazone decreases blood pressure and renal injury in a female mouse model of systemic lupus erythematosus

Women with systemic lupus erythematosus (SLE) exhibit a high prevalence of hypertension and renal injury. Rosiglitazone (Rosi), a peroxisome proliferator activator receptor gamma (PPARγ) agonist, has renal protective and antihypertensive effects. We tested whether Rosi ameliorates hypertension and r...

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Autori principali: Venegas-Pont, Marcia, Sartori-Valinotti, Julio C., Maric, Christine, Racusen, Lorraine C., Glover, Porter H., McLemore, Gerald R., Jones, Allison V., Reckelhoff, Jane F., Ryan, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
Soggetti:
Water and Electrolyte Homeostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698614/
https://ncbi.nlm.nih.gov/pubmed/19193937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90992.2008
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