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T1R2 and T1R3 subunits are individually unnecessary for normal affective licking responses to polycose: implications for saccharide taste receptors in mice

The T1R2 and T1R3 proteins are expressed in taste receptor cells and form a heterodimer binding with compounds described as sweet by humans. We examined whether Polycose taste might be mediated through this heterodimer by testing T1R2 knockout (KO) and T1R3 KO mice and their wild-type (WT) littermat...

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Autors principals: Treesukosol, Yada, Blonde, Ginger D., Spector, Alan C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698609/
https://ncbi.nlm.nih.gov/pubmed/19158407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90869.2008
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