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Kaposi's Sarcoma-Associated Herpesvirus RTA Promotes Degradation of the Hey1 Repressor Protein through the Ubiquitin Proteasome Pathway

The Kaposi's sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) protein regulates the latent-lytic switch by transactivating a variety of KSHV lytic and cellular promoters. RTA is a novel E3 ubiquitin ligase that targets a number of transcriptional repressor pro...

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Autori principali: Gould, Faye, Harrison, Sally M., Hewitt, Eric W., Whitehouse, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698570/
https://ncbi.nlm.nih.gov/pubmed/19369342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00351-09
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