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Activated Ras/MEK Inhibits the Antiviral Response of Alpha Interferon by Reducing STAT2 Levels

The ability of interferon (IFN) to induce the expression of antiviral genes, and therefore suppress viral infection, is dependent on the activity of cellular suppressors. The Ras/MEK pathway is one of these cellular suppressors, since the activation of Ras/MEK permits viral replication in the presen...

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Detaylı Bibliyografya
Asıl Yazarlar: Christian, Sherri L., Collier, Thaddeus W., Zu, Dong, Licursi, Maria, Hough, Chris M., Hirasawa, Kensuke
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698556/
https://ncbi.nlm.nih.gov/pubmed/19386709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02213-08
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