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Combination of the anti-tumour cell ether lipid edelfosine with sterols abolishes haemolytic side effects of the drug

Edelfosine (1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine) is an anti-tumour cell ether lipid with surface-active properties. Pure edelfosine can be dispersed in aqueous media in the form of micelles. One important, negative side effect of edelfosine is that it is highly haemolytic. In this...

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Main Authors: Busto, Jon V., del Canto-Jañez, Esther, Goñi, Félix M., Mollinedo, Faustino, Alonso, Alicia
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698323/
https://ncbi.nlm.nih.gov/pubmed/19568801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-008-0009-z
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