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Downregulation of Wnt signaling is an early signal for formation of facultative heterochromatin and onset of cell senescence in primary human cells

Cellular senescence is an irreversible proliferation arrest of primary cells and an important tumor suppression process. Senescence is often characterized by domains of facultative heterochromatin, called Senescence-Associated Heterochromatin Foci (SAHF), which repress expression of proliferation-pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Ye, Xiaofen, Zerlanko, Brad, Kennedy, Alyssa, Banumathy, Gowrishankar, Zhang, Rugang, Adams, Peter D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698096/
https://ncbi.nlm.nih.gov/pubmed/17643369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.05.034
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