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Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses

Recent research links diet-induced obesity (DIO) with impaired immunity, although the underlying mechanisms remain unclear. We find that the induction of inducible NO synthase (iNOS) and cytokines is suppressed in mice with DIO and in bone marrow macrophages (BMMΦ) from mice with DIO exposed to an o...

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Detalhes bibliográficos
Main Authors: Zhou, Qingde, Leeman, Susan E., Amar, Salomon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697902/
https://ncbi.nlm.nih.gov/pubmed/19541650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904412106
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