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LXRα functions as a cAMP-responsive transcriptional regulator of gene expression

LXRα is a member of a nuclear receptor superfamily that regulates transcription. LXRα forms a heterodimer with RXRα, another member of this family, to regulate the expression of cholesterol 7α-hydroxylase by means of binding to the DR4-type cis-element. Here, we describe a function for LXRα as a cAM...

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Détails bibliographiques
Auteurs principaux: Tamura, Kouichi, Chen, Yuqing E., Horiuchi, Masatsugu, Chen, Qin, Daviet, Laurent, Yang, Zhiyong, Lopez-Ilasaca, Marco, Mu, Hui, Pratt, Richard E., Dzau, Victor J.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC26979/
https://ncbi.nlm.nih.gov/pubmed/10890879
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