Pharmacological characterization of the new histamine H(4) receptor agonist VUF 8430

BACKGROUND AND PURPOSE: We compare the pharmacological profiles of a new histamine H(4) receptor agonist 2-(2-guanidinoethyl)isothiourea (VUF 8430) with that of a previously described H(4) receptor agonist, 4-methylhistamine. EXPERIMENTAL APPROACH: Radioligand binding and functional assays were perf...

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Bibliografiske detaljer
Main Authors: Lim, Herman D, Adami, Maristella, Guaita, Elena, Werfel, Thomas, Smits, Rogier A, de Esch, Iwan JP, Bakker, Remko A, Gutzmer, Ralf, Coruzzi, Gabriella, Leurs, Rob
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2009
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697786/
https://ncbi.nlm.nih.gov/pubmed/19413569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00200.x
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