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Identification of the amino acid residues in the extracellular domain of rat P2X(7) receptor involved in functional inhibition by acidic pH

BACKGROUND AND PURPOSE: P2X(7) receptors are potently inhibited by extracellular acidification. The underlying molecular basis remains unknown. This study aimed to examine the role of extracellular histidine, lysine, aspartic acid and glutamic acid residues in the functional inhibition of rat P2X(7)...

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Bibliografiske detaljer
Main Authors: Liu, X, Ma, W, Surprenant, A, Jiang, L-H
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697781/
https://ncbi.nlm.nih.gov/pubmed/19068080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00002.x
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