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Identification of the amino acid residues in the extracellular domain of rat P2X(7) receptor involved in functional inhibition by acidic pH
BACKGROUND AND PURPOSE: P2X(7) receptors are potently inhibited by extracellular acidification. The underlying molecular basis remains unknown. This study aimed to examine the role of extracellular histidine, lysine, aspartic acid and glutamic acid residues in the functional inhibition of rat P2X(7)...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697781/ https://ncbi.nlm.nih.gov/pubmed/19068080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00002.x |
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