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Do gene polymorphisms alone or in combination affect the function of human β(3)-adrenoceptors?

BACKGROUND AND PURPOSE: β(3)-Adrenoceptors mediate many important physiological functions, for example, in the urinary bladder. The corresponding gene is polymorphic, and the W64R (Trp64Arg) single nucleotide polymorphism has been associated with disease states such as obesity, type 2 diabetes and b...

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Autori principali: Vrydag, Wim, Alewijnse, Astrid E, Michel, Martin C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697764/
https://ncbi.nlm.nih.gov/pubmed/19133996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00014.x
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